Witryna13 sty 2024 · Systemic therapy regimens that contain immune checkpoint blockade immunotherapy, primarily monoclonal antibodies directed against PD-1, PD-L1, or CTLA-4, can induce substantial therapeutic responses in patients with advanced non-small-cell lung cancer (NSCLC). With immune checkpoint blockade, improved survival … WitrynaMy research focused on immune suppression in the tumor microenvironment, where I developed a novel immunotherapy approach to treat cancer. During the summer of 2024, as an AAAS Mass Media fellow, I was a science writer at El Nuevo Día Newspaper in Puerto Rico, where I developed effective writing and communication strategies to …
Practice-Changing Trials Expand Armamentarium and Improve …
Witryna13 lip 2024 · Pembrolizumab is an immunotherapy, called an anti-PD-1 or a checkpoint inhibitor, and is an antibody (a type of human protein) designed to allow the body's own immune system to seek out and destroy tumors. ... Saci-IO TNBC: Randomized Phase II Study of Sacituzumab Govitecan With or Without Pembrolizumab in PD-L1-negative … WitrynaMUC4, an easily measured glycoprotein on the cell surface of approximately one third of women with HER2+ or TNBC, predicts poor survival and treatment resistant disease with increased metastatic potential. ... improves function of trastuzumab based immunotherapies, increases anti-tumor macrophage function, increases tumor … green bay wi fireworks 2021
Merck Named One of Fortune
Witryna13 kwi 2024 · Triple-negative breast cancer (TNBC) is the most aggressive and lethal breast cancer (BC) subtype. 1 Chemotherapy still represents the backbone of the first-line treatment for patients with advanced TNBC (aTNBC). In patients with programmed death-ligand 1 (PD-L1)-negative aTNBC, single-agent or combination chemotherapy … Witryna13 lut 2024 · The excellent outcome observed in the absence of chemotherapy in patients with high TILs, and early-stage TNBC has led to the design of neoadjuvant … Witryna3 lip 2024 · 1. Cortes J. Cescon DW. Rugo HS. et al. Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent … green bay wi fire