Phenoscanner gwas

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August undefined, 2024

WebUsing GWAS analysis in PhenoScanner, we showed that rs7805747 is not only associated with CKD, but also is significantly associated with other diseases or phenotypes. Using metabolite analysis in PhenoScanner, rs7805747 is identified to be significantly associated with not only the serum creatinine, but also with other 16 metabolites. WebEndocrinology - Metabolism. Family Medicine. Internal Medicine. Ophthalmology. Optometry. Pediatrics. Rheumatology. Vascular Surgery

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WebFeb 16, 2024 · Data sources and IVs selection. Detailed information on the data sources were shown in Table 1.Summary-level data of OSA were retrieved from a recent genome-wide association study (GWAS) published by Strausz et al., containing 16,761 OSA patients and 201,194 cases in the FinnGen Study [].Cases of OSA were defined based on the … WebJul 10, 2024 · When selecting SNPs from the GWAS, especially in very large GWAS, it can be difficult to determine whether a SNP has its primary association with the exposure being … grocery stores near arnold afs

Causal association between asthma and periodontitis: A …

WebA tag already exists with the provided branch name. Many Git commands accept both tag and branch names, so creating this branch may cause unexpected behavior. WebJun 18, 2024 · Here, we conduct a genome-wide association study (GWAS) of vitamin B12 deficiency due to lack of intrinsic factor to evaluate the contribution of genetic variation to … file for workman\u0027s comp

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WebPhenoScanner A database of human genotype-phenotype associations Search Catalogue: p -value: Proxies: r 2: Build: Examples: rs10840293 , chr11:9751196 , chr11:9500000 … PhenoScanner is a curated database holding publicly available results from … PhenoScanner is a curated database holding publicly available results from … *Upload a file with either 100 SNPs, 10 genes or 10 genomic regions. Copyright … Studies - PhenoScanner - University of Cambridge The phenoscanner R package allows users to query the PhenoScanner database … Some of the processed data contained within PhenoScanner are available to … The data used in PhenoScanner were obtained from: the GTEx Portal on … 01/01/2024 - PhenoScanner V2 official release. 20/12/2024 - eQTLGen data was … Rs10840293 - PhenoScanner - University of Cambridge Webphenoscanner: PhenoScanner Description The phenoscanner function queries the PhenoScanner database of genotype-phenotype associations from inside R. Usage … file for windowshttp://www.phenoscanner.medschl.cam.ac.uk/?query=rs10840293&catalogue=GWAS&p=1E-5&proxies=None&r2=1&build=37 grocery stores near alanson mi

"WebNov 4, 2024 · (C) Additional MR analyses using SNPs associated (p < 10 −6) with SLE in the Immunochip and GWAS study (rows 1 and 2) or Phenoscanner reaching genome-wide significance (p < 5 × 10 −8, row 3) were used as IVs; summary statistics for the exposure and outcome are indicated. MR analyses excluding the entire short arm of chromosome 6 and ... " - Phenoscanner gwas

Phenoscanner gwas

Mendelian randomization and pathway analysis demonstrate …

Web5000 datasets examined over 100 traits (www.phenoscanner.medschl. cam.ac.uk/)] (9). Other PheWAS databases are constructed on the basis of polygenic scores estimated from multiple variants per GWAS locus (10), latent factors underlying groups of variants (11), or vari-ants overlapping between GWAS and PheWAS catalogs (12). By WebApr 11, 2024 · 在欧洲人群中使用全基因组关联研究（gwas）的汇总统计进行了mr研究，并在东亚裔个体中复制了结果。covid-19最大的gwas数据来自基于covid-19宿主遗传学倡议的最新r7版本。于sle的结果，meta-gwas产生了迄今为止最大的gwas汇总统计，由14267人组成。 …

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WebJun 24, 2024 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies in humans. This online tool facilitates "phenome scans", where genetic variants are... WebApr 12, 2024 · We searched summary-level GWAS data collated by PhenoScanner 22 and the IEU OpenGWAS 23 to identify whether SNPs used to instrument G. Bifidobacterium …

WebMay 11, 2024 · Genetic associations for lipid traits have identified hundreds of variants with clear differences across European, Asian and African studies. Based on a sub-Saharan-African GWAS for lipid traits in the population cross-sectional AWI-Gen cohort (N = 10,603) we report a novel LDL-C association in the GATB region (P-value=1.56 × 10 −8).Meta … WebNov 1, 2024 · RegulomeDb, GWAS Central, GTEx and PhenoScanner depicted the involvement of ULK1 gene in various parts of brain leading to various mental disorders. The interaction of ULK1 gene and its pathway analysis showed that ULK1 gene interacts with various other genes like ATG, mTOR, RPTOR and many more involved in autophagy …

WebOct 15, 2016 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies. This tool aims to facilitate 'phenome scans', the cross-referencing of genetic variants with many phenotypes, to help aid understanding of disease pathways and biology. The database currently contains over 350 million association ... WebSep 10, 2024 · Using PhenomeXcan results, we provide examples of novel and underreported genome-to-phenome associations, complex gene-trait clusters, shared …

WebJun 14, 2024 · 研究中可作iv 使用的snp位点较少，这可能是呼吸系统和神经系统之间遗传背景相差较大导致的。此外，研究所使用的gwas数据都来自欧洲人群，而且csvd只有白质损伤相关表型的gwas数据有开放获取的途径，这些都造成研究结果的局限性。

Web微信公众号医学论文与统计分析介绍：本公众号高校统计学老师所设，重点介绍为SPSS数据分析方法、真实世界研究、m论文写作、R语言与数据挖掘。关注后，发送关键词“33”到公众号就可以获取常见的统计软件比如Spss，sas，PASS（绝对无毒）；孟德尔随机化丨IF=38.64，没有因果关系也能发高分文章！ file for workers compensation exemption in flWebJun 17, 2016 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies. This tool aims to facilitate 'phenome scans', the cross-referencing of genetic variants with many phenotypes, to help aid understanding of disease pathways and biology. ... (GWAS) have discovered thousands of associations between ... file for workers compWebApr 11, 2024 · 在欧洲人群中使用全基因组关联研究（gwas）的汇总统计进行了mr研究，并在东亚裔个体中复制了结果。covid-19最大的gwas数据来自基于covid-19宿主遗传学倡议的 … file for windows security to trust publisherWebAn introduction to our ancestry curation process. As of , the GWAS Catalog contains publications, top associations and full summary statistics. GWAS Catalog data is … file for workman\u0027s compensationWebSep 26, 2024 · Both heritability analysis and GWAS models were adjusted for age, sex, height, weight, systolic blood pressure corrected for antihypertensive medication use (by adding 15 mm Hg), phenotype-derivation method (automatic/manual), array type (UK Biobank versus UK BiLEVE array), and imaging center ( Methods in the online-only Data … grocery stores near altoonaWebApr 12, 2024 · Searching GWAS summary statistics collated by PhenoScanner found evidence for potential horizontal pleiotropy between the SNP used as an instrument for G. Bifidobacterium (rs4988235) and CRC risk. file for your fflWebDec 20, 2024 · Results: The MR set parallel GWAS cohorts, among which, those involved in the primary analysis were comprised of 337 234 participants for physical activity and 158 025 participants (29 531 cases) for CBP. ... We searched PhenoScanner database for these SNPs and found that the most potential pleiotropy was “trunk fat/fat-free mass”, which ... file for workers compensation ohio